Author

A. Shelton

University of Utah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. B. Satterlee· 1 shared A. K. Grosskopf· 1 shared A. l. d'Aquino· 1 shared A. Sathe· 1 shared Ayden Berndt· 1 shared B. E. Mann· 1 shared B. Lee· 1 shared C. Ayala· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. B. Satterlee

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Author profile →

4 papers

Recent·Most cited

Positron Emission Tomography of CD47/SIRPα Axis and Image-Informed Therapeutic Design

Esther Need, Neetu Singh, Ayden Berndt, A. Shelton, Samuel Henry Cheshier, Shreya Goel, Sixiang Shi

The paper develops radiotracers for CD47/SIRPα axis imaging and evaluates their biodistribution in mice, showing potential for optimizing therapeutic strategies.

bioRxiv · Jan 29, 2026 · PreprintBioengineering

Trans-Lesion Synthesis and Mismatch Repair Pathway Crosstalk Defines Chemoresistance and Hypermutation Mechanisms in Glioblastoma

X. Cheng, J. An, J. Lou, Q. Gu, W. Ding, G. Droby, Y. Wang, C. Wang, Y. Gao, A. Shelton, A. B. Satterlee, B. E. Mann, Y.-C. Hsiao, C.-W. Liu, K. Liu, , Y. Yang

This study identifies RAD18's role in TMZ resistance and hypermutation in GBM by linking it to TLS and MMR pathways through CRISPR screening and mutation analysis.

bioRxiv · Oct 16, 2023 · PreprintCancer Biology

GITR and TIGIT immunotherapy provokes divergent multi-cellular responses in the tumor microenvironment of gastrointestinal cancers

A. Sathe, C. Ayala, X. Bai, S. M. Grimes, B. Lee, C. Kin, A. Shelton, G. Poultsides, H. Ji

The paper examines GITR and TIGIT immunotherapies in gastrointestinal cancers using ex vivo cultures and single-cell sequencing to identify their cellular mechanisms in the tumor microenvironment.

bioRxiv · Mar 13, 2023 · PreprintCancer Biology

Injectable polymer-nanoparticle hydrogel for the sustained intravitreal delivery of bimatoprost

E. L. Meany, R. Andaya, S. Tang, C. M. Kasse, R. N. Fuji, A. K. Grosskopf, A. l. d'Aquino, J. T. Bartoe, R. Ybarra, A. Shelton, Z. Pederson, C. Hu, D. Leung, K. Nagapudi, S. Ubhayakar, , E. Appel

This paper develops an injectable polymer-nanoparticle hydrogel for sustained intravitreal delivery of bimatoprost, showing prolonged drug release and minimal inflammation in rabbits.

bioRxiv · Sep 8, 2022Bioengineering