Author

C. M. Kasse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 2 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. K. Grosskopf· 2 shared E. Appel· 2 shared A. Buahin· 1 shared A. C. Yu· 1 shared A. E. Powell· 1 shared A. I. d'Aquino· 1 shared A. l. d'Aquino· 1 shared A. Shelton· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

A. K. Grosskopf

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3 papers

Recent·Most cited

Injectable polymer-nanoparticle hydrogel for the sustained intravitreal delivery of bimatoprost

E. L. Meany, R. Andaya, S. Tang, C. M. Kasse, R. N. Fuji, A. K. Grosskopf, A. l. d'Aquino, J. T. Bartoe, R. Ybarra, A. Shelton, Z. Pederson, C. Hu, D. Leung, K. Nagapudi, S. Ubhayakar, , E. Appel

This paper develops an injectable polymer-nanoparticle hydrogel for sustained intravitreal delivery of bimatoprost, showing prolonged drug release and minimal inflammation in rabbits.

bioRxiv · Sep 8, 2022Bioengineering

Stable High-Concentration Monoclonal Antibody Formulations Enabled by an Amphiphilic Copolymer Excipient

J. H. Klich, C. M. Kasse, J. L. Mann, Y. Huang, A. I. d'Aquino, A. K. Grosskopf, J. Baillet, G. G. Fuller, E. Appel

This paper introduces an amphiphilic copolymer excipient that enhances the stability of high-concentration monoclonal antibody formulations without affecting pharmacokinetics or injectability.

bioRxiv · May 25, 2022Bioengineering

Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot

C. M. Kasse, A. C. Yu, A. E. Powell, G. A. Roth, C. S. Liong, C. K. Jons, A. Buahin, C. L. Maikawa, S. Youssef, J. E. Glanville, E. A. Appel

This paper develops a supramolecular hydrogel depot for subcutaneous delivery of SARS-CoV-2 bnAbs, showing prolonged release and improved pharmacokinetics compared to standard administration.

bioRxiv · May 24, 2022Bioengineering