Author

A. Spektor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

D. Pellman· 2 shared A. M. Cheng· 1 shared B. Cheng· 1 shared C. Yapp· 1 shared C.-Z. Zhang· 1 shared G. J. Baker· 1 shared H. F. Almubarak· 1 shared J. B. Tefft· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

D. Pellman

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Author profile →

2 papers

Recent·Most cited

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

S. Coy, B. Cheng, J. S. Lee, R. Rashid, L. Browning, Y. Xu, S. S. Chakrabarty, C. Yapp, S. Chan, J. B. Tefft, A. Spektor, K. L. Ligon, G. J. Baker, D. Pellman, P. K. Sorger, S. Santagata

The paper shows nuclear rupture is common in cancer, especially glioblastoma, and links it to lamin proteins and immune signaling.

bioRxiv · Nov 7, 2023 · PreprintCancer Biology

Mechanisms Generating Cancer Genome Complexity From A Single Cell Division Error

N. Umbreit, C.-Z. Zhang, L. D. Lynch, L. J. Blaine, A. M. Cheng, R. W. Tourdot, L. Sun, H. F. Almubarak, K. Judge, T. J. Mitchell, A. Spektor, D. Pellman

This study identifies a mutational cascade triggered by chromosome bridge formation that leads to chromothripsis and contributes to cancer genome complexity and sub-clonal heterogeneity.

bioRxiv · Nov 7, 2019Cancer Biology