Author

C.-Z. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Pellman· 2 shared R. W. Tourdot· 2 shared A. M. Cheng· 1 shared A. Sadagopan· 1 shared A. Spektor· 1 shared B. van Steensel· 1 shared C. Bao· 1 shared D. Freeman· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

D. Pellman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma

M. Achom, A. Sadagopan, C. Bao, F. McBride, Q. Xu, P. Konda, R. W. Tourdot, J. Li, M. Nakhoul, D. Gallant, U. A. Ahmed, J. O'Toole, D. Freeman, G.-S. M. Lee, J. Hecht, , S. R. Viswanathan

This study identifies a genetic basis for cancer sex differences in Xp11 translocation renal cell carcinoma by showing a 2:1 female:male ratio in TFE3 fusions involving the inactive X chromosome.

bioRxiv · Aug 4, 2023 · PreprintCancer Biology

Extinction drives a discontinuous temporal pattern of species-area relationships in a microbial microcosm system

W. Deng, N. Li, C.-Z. Zhang, R. An, X.-Y. Yang, W. Xiao

This study shows that extinction drives a temporally discontinuous species-area relationship in microbial microcosms, with small-scale extinctions promoting stability and mass extinctions resetting the system.

bioRxiv · Nov 11, 2022Ecology

Transgenerational transcriptional heterogeneity from cytoplasmic chromatin

S. Papathanasiou, N. A. Mynhier, S. Liu, E. Jacob, E. Stokasimov, B. van Steensel, C.-Z. Zhang, D. Pellman

This study shows that micronuclei can cause heritable transcriptional changes by disrupting chromatin states, even after chromosomes are reincorporated into normal nuclei.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

Mechanisms Generating Cancer Genome Complexity From A Single Cell Division Error

N. Umbreit, C.-Z. Zhang, L. D. Lynch, L. J. Blaine, A. M. Cheng, R. W. Tourdot, L. Sun, H. F. Almubarak, K. Judge, T. J. Mitchell, A. Spektor, D. Pellman

This study identifies a mutational cascade triggered by chromosome bridge formation that leads to chromothripsis and contributes to cancer genome complexity and sub-clonal heterogeneity.

bioRxiv · Nov 7, 2019Cancer Biology