Author

A. Tavakkoli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:metabolism & bioenergetics· 3 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

E. G. Sheu· 4 shared D. A. Harris· 3 shared R. Subramaniam· 3 shared T. Lo· 3 shared A. S. Banks· 2 shared A. Elkhal· 1 shared A. H. Vernon· 1 shared A. Mina· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersCancer Biology

E. G. Sheu

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Sleeve gastrectomy promotes colitis-associated colorectal cancer in a murine model via a modified gut microbiome

J. N. Luo, R. S. Haridas, T. Lo, A. Tavakkoli, J. Yoo, E. G. Sheu

This study shows that sleeve gastrectomy worsens colitis-associated colorectal cancer in mice by altering the gut microbiome, which can independently promote tumor growth.

bioRxiv · Jun 4, 2022 · PreprintCancer Biology

Daily transient coating of the intestine leads to weight loss and improved glucose tolerance

T. Lo, Y. Lee, C.-Y. Tseng, Y. Hu, C. Mantzoros, J. Karp, A. Tavakkoli

This study shows that daily administration of LuCI, an oral gut coating agent, leads to weight loss and improved insulin sensitivity in a rat model of diet-induced obesity.

bioRxiv · Jun 11, 2021Bioengineering

Restored TDCA and Valine Levels Imitate the Effects of Bariatric Surgery

S. G. Tullius, M. Quante, J. Iske, T. Heinbokel, B. N. Desai, H. R. C. Biefer, Y. Nian, F. Krenzien, H. Uehara, R. Maenosono, H. Azuma, J. Pratschke, C. Falk, T. Lo, E. Sheu, , A. Elkhal

The paper shows that restoring TDCA and valine levels in obese mice mimics the weight loss effects of bariatric surgery.

bioRxiv · Jan 11, 2021Cell Biology

Weight and organ specific immune cell profiling of Sleeve Gastrectomy

D. A. Harris, R. Subramaniam, T. Brenner, A. Tavakkoli, E. G. Sheu

This study uses CyTOF to analyze organ-specific immune cell changes after sleeve gastrectomy in mice, finding shifts in B cell subsets, increased neutrophils, and M2 macrophage polarization linked to metabolic improvements.

bioRxiv · Jun 28, 2020Immunology

Bariatric surgery reveals a gut-restricted TGR5 agonist that exhibits anti-diabetic effects

S. N. Chaudhari, D. A. Harris, H. Aliakbarian, M. T. Henke, R. Subramaniam, A. H. Vernon, A. Tavakkoli, E. G. Sheu, A. S. Devlin

This study identifies CA7S, a gut-restricted TGR5 agonist that improves glucose tolerance in insulin-resistant mice by inducing GLP-1 secretion.

bioRxiv · Jan 10, 2020Biochemistry

Sleeve Gastrectomy enhances glucose utilization and remodels adipose tissue independent of weight loss

D. A. Harris, A. Mina, D. Cabarkapa, K. Heshmati, R. Subramaniam, A. S. Banks, A. Tavakkoli, E. G. Sheu

This study shows that sleeve gastrectomy improves glucose utilization and remodels adipose tissue metabolism without causing weight loss in mice.

bioRxiv · Sep 23, 2019Physiology