Author

S. N. Chaudhari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. S. Devlin· 4 shared A. A. Adhikari· 3 shared A. S. Banks· 2 shared D. Ramachandran· 2 shared M. D. McCurry· 2 shared A. H. Vernon· 1 shared A. Tavakkoli· 1 shared C. E. Powell· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

A. S. Devlin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury

D. K. Li, S. N. Chaudhari, M. Sojoodi, Y. Li, A. A. Adhikari, L. Zukerberg, S. Shroff, S. C. Barrett, K. Tanabe, R. T. Chung, A. S. Devlin

bioRxiv · Mar 24, 2021Physiology

A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases

A. A. Adhikari, D. Ramachandran, S. N. Chaudhari, C. E. Powell, M. D. McCurry, A. S. Banks, A. S. Devlin

The paper develops a gut-restricted BSH inhibitor, AAA-10, which effectively reduces secondary bile acids in mice with minimal systemic exposure.

bioRxiv · Mar 15, 2021Biochemistry

Bariatric surgery reveals a gut-restricted TGR5 agonist that exhibits anti-diabetic effects

S. N. Chaudhari, D. A. Harris, H. Aliakbarian, M. T. Henke, R. Subramaniam, A. H. Vernon, A. Tavakkoli, E. G. Sheu, A. S. Devlin

This study identifies CA7S, a gut-restricted TGR5 agonist that improves glucose tolerance in insulin-resistant mice by inducing GLP-1 secretion.

bioRxiv · Jan 10, 2020Biochemistry

Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases

A. A. Adhikari, T. C. Seegar, S. B. Ficarro, M. D. McCurry, D. Ramachandran, L. Yao, S. N. Chaudhari, S. Ndousse-Fetter, A. S. Banks, J. A. Marto, S. C. Blacklow, A. S. Devlin

This study develops a covalent inhibitor of gut bacterial bile salt hydrolases, showing it reduces BSH activity and deconjugated bile acids in mice.

bioRxiv · May 17, 2019Microbiology