Author

A. S. Banks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 7 Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 3 Research Focus:metabolism & bioenergetics· 3 Assay:bulk RNA-seq· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. Ramachandran· 4 shared A. A. Adhikari· 2 shared A. S. Devlin· 2 shared A. Tavakkoli· 2 shared M. D. McCurry· 2 shared S. N. Chaudhari· 2 shared A. Elkhal· 1 shared A. Gulko· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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4 shared papersCell Biology

D. Ramachandran

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

GDF3 is an obesity-induced regulator of TGFβ superfamily signaling

D. Ramachandran, N. Kotikalapudi, G. R. Gipson, L. Troncone, K. Vestal, D. E. Maridas, A. Gulko, L. T. Tsai, V. Rosen, P. B. Yu, T. B. Thompson, A. S. Banks

This study identifies GDF3 as an obesity-induced regulator that modulates TGFβ superfamily signaling by inhibiting BMP and activating activin-like SMAD 2/3 pathways in adipose tissue.

bioRxiv · Nov 7, 2022 · PreprintCell Biology

Absence of muricholic acid due to Cyp2c-deficiency protects against high fat diet-induced obesity in male mice but promotes liver damage

A.-B. Oteng, S. Higuchi, A. S. Banks, R. A. Haeusler

This study shows that Cyp2c-deficient mice are protected from obesity on a high fat diet but experience increased liver damage, suggesting MCAs may protect against liver injury rather than obesity.

bioRxiv · May 10, 2021Physiology

A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases

A. A. Adhikari, D. Ramachandran, S. N. Chaudhari, C. E. Powell, M. D. McCurry, A. S. Banks, A. S. Devlin

The paper develops a gut-restricted BSH inhibitor, AAA-10, which effectively reduces secondary bile acids in mice with minimal systemic exposure.

bioRxiv · Mar 15, 2021Biochemistry

Restored TDCA and Valine Levels Imitate the Effects of Bariatric Surgery

S. G. Tullius, M. Quante, J. Iske, T. Heinbokel, B. N. Desai, H. R. C. Biefer, Y. Nian, F. Krenzien, H. Uehara, R. Maenosono, H. Azuma, J. Pratschke, C. Falk, T. Lo, E. Sheu, , A. Elkhal

The paper shows that restoring TDCA and valine levels in obese mice mimics the weight loss effects of bariatric surgery.

bioRxiv · Jan 11, 2021Cell Biology

A big-data approach to understanding metabolic rate and response to obesity in laboratory mice

J. K. Corrigan, D. Ramachandran, Y. He, C. Palmer, M. J. Jurczak, B. Li, R. H. Friedline, J. K. Kim, J. J. Ramsey, L. Lantier, O. P. McGuinness, A. S. Banks, Mouse Metabolic Phenotyping Center Energy Balance Working Group

This study analyzes indirect calorimetry data from thousands of mice to identify sources of metabolic variation and provides guidelines for designing and reporting metabolic experiments.

eLife · May 1, 2020Peer-reviewedPhysiology

Sleeve Gastrectomy enhances glucose utilization and remodels adipose tissue independent of weight loss

D. A. Harris, A. Mina, D. Cabarkapa, K. Heshmati, R. Subramaniam, A. S. Banks, A. Tavakkoli, E. G. Sheu

This study shows that sleeve gastrectomy improves glucose utilization and remodels adipose tissue metabolism without causing weight loss in mice.

bioRxiv · Sep 23, 2019Physiology

Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases

A. A. Adhikari, T. C. Seegar, S. B. Ficarro, M. D. McCurry, D. Ramachandran, L. Yao, S. N. Chaudhari, S. Ndousse-Fetter, A. S. Banks, J. A. Marto, S. C. Blacklow, A. S. Devlin

This study develops a covalent inhibitor of gut bacterial bile salt hydrolases, showing it reduces BSH activity and deconjugated bile acids in mice.

bioRxiv · May 17, 2019Microbiology