Author

A. Tracz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

D. G. Tang· 3 shared G. Chatta· 2 shared I. Puzanov· 2 shared J. Wang· 2 shared S. Liu· 2 shared X. Liu· 2 shared Y. Ji· 2 shared A. Carracedo· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

D. G. Tang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Developing folate-conjugated miR-34a therapeutic for prostate cancer treatment: Challenges and promises

W. Li, Y. Wang, X. Liu, S. Wu, M. Wang, S. G. Turowski, J. A. Spernyak, A. Tracz, A. M. Abdelaal, K. Sudarshan, I. Puzanov, G. Chatta, A. L. Kasinski, D. G. Tang

This study evaluates folate-conjugated miR-34a as a potential prostate cancer therapeutic, finding limited efficacy due to low FOLR1 expression in prostate cancer cells.

bioRxiv · Nov 25, 2023 · PreprintCancer Biology

Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells

J. S. Kirk, J. Wang, A. Tracz, M. Long, S. R. Rosario, Y. Ji, R. Kumar, X. Liu, P. K. Singh, I. Puzanov, G. Chatta, Q. Cheng, J. Huang, J. L. Wrana, J. Lovell, , D. G. Tang

The paper uses multi-omics single-cell data to define the epigenetic basis of castration-resistant prostate luminal cells in mice and identifies key molecular pathways involved.

bioRxiv · Mar 3, 2023Cancer Biology

STAT3 restricts prostate cancer metastasis and antiandrogen resistance by controlling LKB1/CREB signaling pathway

J. Pencik, C. Philippe, M. Schlederer, M. Pecoraro, S. Grund-Groeschke, W. J. Li, A. Tracz, I. Heidegger, S. Lagger, K. Trachtova, M. Oberhuber, E. Heitzer, O. Osman, H. A. Neubauer, B. Wingelhofer, , C. McKinney

This study identifies STAT3's role in restricting prostate cancer metastasis and antiandrogen resistance by regulating the LKB1/CREB signaling pathway in mouse models and human patients.

bioRxiv · Aug 25, 2022 · PreprintCancer Biology

Dysregulated Alternative Splicing Landscape Identifies Intron Retention as a Hallmark and Spliceosome as a Therapeutic Vulnerability in Aggressive Prostate Cancer

D. Zhang, Q. Hu, Y. Ji, H.-P. Chao, A. Tracz, J. Kirk, S. Buonamici, P. Zhu, J. Wang, S. Liu, D. G. Tang

The paper identifies intron retention as a hallmark of aggressive prostate cancer and highlights the spliceosome as a therapeutic target by analyzing splicing dysregulation across prostate cancer progression.

bioRxiv · May 11, 2019 · PreprintCancer Biology