Author

D. G. Tang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Tracz· 3 shared G. Chatta· 2 shared I. Puzanov· 2 shared J. Wang· 2 shared S. Liu· 2 shared S. Wu· 2 shared X. Liu· 2 shared Y. Ji· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

A. Tracz

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Author profile →

4 papers

Recent·Most cited

Developing folate-conjugated miR-34a therapeutic for prostate cancer treatment: Challenges and promises

W. Li, Y. Wang, X. Liu, S. Wu, M. Wang, S. G. Turowski, J. A. Spernyak, A. Tracz, A. M. Abdelaal, K. Sudarshan, I. Puzanov, G. Chatta, A. L. Kasinski, D. G. Tang

This study evaluates folate-conjugated miR-34a as a potential prostate cancer therapeutic, finding limited efficacy due to low FOLR1 expression in prostate cancer cells.

bioRxiv · Nov 25, 2023 · PreprintCancer Biology

AP-1 regulates heterogeneous cellular dormancy in TNBC

Y. Dong, J. Bai, R. Fu, H. Su, S. Wu, R. N. Liu, D. G. Tang, J. Zhou

The paper identifies heterogeneous subpopulations of slow-cycling cells in TNBC and shows AP-1, particularly the JunB subunit, regulates dormancy and drug resistance.

bioRxiv · Nov 22, 2023 · PreprintCancer Biology

Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells

J. S. Kirk, J. Wang, A. Tracz, M. Long, S. R. Rosario, Y. Ji, R. Kumar, X. Liu, P. K. Singh, I. Puzanov, G. Chatta, Q. Cheng, J. Huang, J. L. Wrana, J. Lovell, , D. G. Tang

The paper uses multi-omics single-cell data to define the epigenetic basis of castration-resistant prostate luminal cells in mice and identifies key molecular pathways involved.

bioRxiv · Mar 3, 2023Cancer Biology

Dysregulated Alternative Splicing Landscape Identifies Intron Retention as a Hallmark and Spliceosome as a Therapeutic Vulnerability in Aggressive Prostate Cancer

D. Zhang, Q. Hu, Y. Ji, H.-P. Chao, A. Tracz, J. Kirk, S. Buonamici, P. Zhu, J. Wang, S. Liu, D. G. Tang

The paper identifies intron retention as a hallmark of aggressive prostate cancer and highlights the spliceosome as a therapeutic target by analyzing splicing dysregulation across prostate cancer progression.

bioRxiv · May 11, 2019 · PreprintCancer Biology