A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells
P. Mondal, G. Alyateem, A. V. Mitchell, M. M. Gottesman
bioRxiv · Feb 15, 2024 · PreprintCancer Biology
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P. Mondal, G. Alyateem, A. V. Mitchell, M. M. Gottesman
bioRxiv · Feb 15, 2024 · PreprintCancer Biology
R. W. Robey, C. M. Fitzsimmons, W. M. Guiblet, W. J. E. Frye, J. Gonzalez Dalmasy, L. Wang, D. A. Russell, L. M. Huff, A. J. Perciaccante, F. Ali-Rahmani, C. C. Lipsey, H. M. Wade, A. V. Mitchell, S. S. Maligireddy, D. Terrero, , P. J. Batista
This study identifies METTL7A and METTL7B as methyltransferases that confer resistance to thiol-based HDAC inhibitors by modifying the drug's zinc-binding thiol.
bioRxiv · Oct 7, 2022Cancer Biology