Reduced ech-6 Expression Attenuates Fat-induced Premature Aging in C. elegans
Y. J. Liu, A. W. Gao, R. L. Smith, G. E. Janssens, D. M. Panneman, A. Jongejan, M. van Weeghel, F. M. Vaz, M. J. Silvestrini, L. R. Lapierre, A. W. MacInnes, R. H. Houtkooper
This study shows that reducing ech-6 expression in C. elegans mitigates fat-induced premature aging, suggesting a role for ech-6 in metabolic flexibility and longevity.
bioRxiv · Nov 2, 2020 · PreprintCell Biology