A. Z. Politi

The paper maps nuclear pore complex assembly in human cells, revealing two distinct molecular mechanisms with different orders of component addition.

The paper measures absolute copy numbers and dynamics of cohesin, CTCF, and related proteins in human cells, revealing that some genomic enrichment sites are unoccupied in single cells.

The paper shows that two spindles form in mammalian zygotes to keep parental genomes apart during the first cleavage.

The paper quantifies Condensin I and II dynamics during mitosis, proposing a three-step loop model for chromosome compaction.

This study investigates the self-assembly of mutant huntingtin exon-1 fragments into complex fibrillar structures, identifying two nucleation mechanisms and their role in fibril formation.