Author

A.-D. Brunner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. Mann· 4 shared M. Thielert· 2 shared A. C. Michaelis· 1 shared A. Erturk· 1 shared A. Palladini· 1 shared B. B. Chhun· 1 shared B. H. Menze· 1 shared B. Huang· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCell Biology

M. Mann

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Author profile →

4 papers

Recent·Most cited

Rapid and in-depth coverage of the (phospho-)proteome with deep libraries and optimal window design for dia-PASEF

P. Skowronek, M. Thielert, E. Voytik, M. C. Tanzer, F. M. Hansen, S. Willems, O. Karayel, A.-D. Brunner, F. Meier, M. Mann

This paper introduces an optimized dia-PASEF method with variable isolation windows to enhance proteome and phosphoproteome coverage in mass spectrometry.

bioRxiv · May 31, 2022Biochemistry

Proteomics of spatially identified tissues in whole organs

H. S. Bhatia, A.-D. Brunner, Z. Rong, H. Mai, M. Thielert, R. Al-Maskari, J. C. Paetzold, F. Kofler, M. I. Todorov, M. Ali, M. Molbay, Z. I. Kolabas, D. Kaltenecker, S. Mueller, S. F. Lichtenthaler, , A. Erturk

This paper introduces DISCO-MS, a method for spatial proteomics of whole organs, and shows it provides proteomics data comparable to fresh tissues in rodent and human samples.

bioRxiv · Nov 2, 2021 · PreprintBioengineering

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

N. H. Cho, K. C. Cheveralls, A.-D. Brunner, K. Kim, A. C. Michaelis, P. Raghavan, H. Kobayashi, L. Savy, J. Y. Li, H. Canaj, J. Y. S. Kim, E. M. Setwart, C. Gnann, F. McCarthy, J. P. Cabrera, , M. D. Leonetti

The paper maps human protein localization and interactions using genome engineering, imaging, and data science, revealing functional communities and RNA-binding protein subgroups.

bioRxiv · Mar 29, 2021Cell Biology

Purification of age-distinct insulin secretory granules through antigen restriction

M. Neukam, P. Sala, A.-D. Brunner, K. Ganss, A. Palladini, M. Grzybek, J. Vasiljevic, J. Broichhagen, U. Coskun, K. Johnsson, T. Kurth, M. Mann, M. Solimena

The paper purifies age-distinct insulin secretory granules from INS-1 cells and identifies age-related changes in their lipid composition and membrane properties.

bioRxiv · Jun 3, 2020Cell Biology