Phosphorylation of CRYAB Induces a Condensatopathy to Worsen Post-Myocardial Infarction Left Ventricular Remodeling.
Moydul Islam, David R. Rawnsley, Xiucui Ma, Walter Navid, Chen Zhao, 关旭民, Layla Foroughi, John T. Murphy, Honora Navid, Carla J. Weinheimer, Attila Kovacs, Jess Nigro, Aaradhya Diwan, Ryan P. Chang, Minu Kumari, , Abhinav Diwan
This study shows that phosphorylation of CRYAB leads to condensate formation and worsens heart failure after myocardial infarction.
Journal of Clinical Investigation · Feb 11, 2025Peer-reviewedCell Biology