Author

Abhishek Saha

Centre for Cellular and Molecular BiologyPrimary ORCID profile (0000-0003-4200-2381 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Abhishek SahaiD1 paper · University of Oxford

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Priyanka DahiyaiD· 2 shared Sangita MukhopadhyayiD· 2 shared Sudip GhoshiD· 2 shared Vinay Kumar NandicooriiD· 2 shared Aakash ChandramouliiD· 1 shared Amit Banerjee· 1 shared Manoj Kumar BishtiD· 1 shared Siddhesh S. KamatiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Priyanka DahiyaORCID

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2 papers

Recent·Most cited

PE11 promotes intracellular persistence of Mycobacterium tuberculosis by inhibiting autophagy and lysosomal biogenesis by targeting the FLCN-lactate-TFEB signaling axis

Priyanka Dahiya, Manoj Kumar Bisht, Abhishek Saha, Aakash Chandramouli, Siddhesh S. Kamat, Vinay Kumar Nandicoori, Sudip Ghosh, Sangita Mukhopadhyay

This study identifies PE11 as a factor that promotes Mtb persistence by inhibiting autophagy and lysosomal biogenesis through the FLCN-lactate-TFEB signaling axis, with lactate shown to enhance bacterial clearance.

bioRxiv · Jul 31, 2025 · PreprintMicrobiology

Structure-function relationship of PE11 esterase of Mycobacterium tuberculosis with respect to its role in virulence

Priyanka Dahiya, Amit Banerjee, Abhishek Saha, Vinay Kumar Nandicoori, Sudip Ghosh, Sangita Mukhopadhyay

This study characterizes the structure and function of PE11 esterase from Mycobacterium tuberculosis, showing its role in virulence and potential as a therapeutic target.

Biochemical and Biophysical Research Communications · Nov 10, 2024Peer-reviewedMicrobiology