Author

Aleksandra Podkowka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna SzlachciciD· 2 shared Daria Gajewska· 2 shared Kamil Przytulski· 2 shared Magdalena Sypien· 2 shared Michał BiśtaiD· 2 shared Michał WalczakiD· 2 shared Agnieszka Maria JeleńiD· 1 shared Alicja N. SkowroniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMolecular Biology

Anna SzlachcicORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Ligand-induced Conformational Plasticity of the CTLH E3 Ligase Receptor GID4

Daria Kotlarek, Katarzyna Dudek, Bartosz Woźniak, Martyna W. Pastok, Dmitrii V. Shishov, Sylvain Cottens, Michał Biśta, Emilia Krzywiecka, Karolina Maria Górecka, Kinga Jurczak, Tomáš Drmota, Justyna Adamczyk, Szymon Faliński, Daria Gajewska, Marta Klejnot, , Michał Walczak

This study designs high-affinity ligands for the E3 ligase GID4 to enable targeted protein degradation, identifying conformational changes and potential degrader structures, though degradation efficacy remains to be optimized.

ChemMedChem · Apr 3, 2026Peer-reviewedMolecular Biology

Expression screen of TNFR1 R347A, MyD88, IRAK4 death domains in E. coli followed by purification and biophysical characterization of TNFR1 R347A death domain

Kamil Przytulski, Aleksandra Podkowka, Tomasz Tomczyk, Daria Gajewska, Magdalena Sypien, Agnieszka Maria Jeleń, Priyanka Dahate, Anna Szlachcic, Michał Biśta, Michał Walczak

The paper optimizes expression and characterizes the stability of TNFR1 R347A, MyD88, and IRAK4 death domains in E. coli.

bioRxiv · Dec 13, 2024 · PreprintBiochemistry