Author

Alexander Chung

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adina H. WiseiD· 1 shared Aloysius DomingoiD· 1 shared Amanda AllaniD· 1 shared Artem SokoloviD· 1 shared Aslı ŞahiniD· 1 shared Benjamin Muller· 1 shared Beomjin JangiD· 1 shared Casey YoungiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adina H. WiseORCID

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2 papers

Recent·Most cited

Integrated Stress Response Signatures Drive Monocyte Dysfunction in GBA1- and LRRK2-Linked Parkinson's Disease

Daniele Mattei, Erica Brophy, Mikaela Rosén, Oriol Narcis Majos, Aloysius Domingo, Elena Meijia, Claudia De Sanctis, Beomjin Jang, Tarek Khashan, Mengxi Yang, Deborah Raymond, Casey Young, Jack Humphrey, Elisa Navarro, Amanda Allan, , Towfique Raj

The paper identifies integrated stress response (ISR) signatures and proteostasis defects in monocytes from GBA1- and LRRK2-linked Parkinson's disease, linking them to immune dysfunction.

medRxiv · Oct 8, 2025 · PreprintGenetic & Genomic Medicine

TYK2 as a novel therapeutic target in Alzheimer Disease

Laura E. König, Steve Rodriguez, Clemens B. Hug, Shayda Daneshvari, Alexander Chung, Gary Andrew Bradshaw, Aslı Şahin, George Zhou, Robyn J. Eisert, Federica Piccioni, Sudeshna Das, Marian Kalocsay, Artem Sokolov, Peter Karl Sorger, David E. Root, Mark W. Albers

The paper identifies TYK2 as a potential therapeutic target for neurodegenerative diseases by linking cdsRNA-induced inflammation to interferon signaling and demonstrating protective effects of TYK2 inhibitors.

bioRxiv · Jun 4, 2024 · PreprintNeuroscience