Author

Alexander Lin

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 2 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Assay:imaging· 3 Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alan R. LoweiD· 1 shared Alex Xijie LuiD· 1 shared Alexander V. HillsleyiD· 1 shared Bin DuaniD· 1 shared Bin Xie· 1 shared Brian C. DeFeliceiD· 1 shared Carolina AriasiD· 1 shared Cassidy JonesiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperSystems Biology

Alan R. LoweORCID

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Author profile →

4 papers

Recent·Most cited

A multimodal perturbation atlas defines the phenotypic resolution of cellular morphology.

Chad Liu, Alexander V. Hillsley, Madhurya Sekhar, Cassidy Jones, Gabriel Sturm, Taihei Fujimori, Diane M. Wiener, Karen W. Cheng, Talon Chandler, Alexander Lin, Duo Peng, Max Frank, Leah C. Dorman, Ilakkiyan Jeyakumar, Ivan E. Ivanov, , Manuel D. Leonetti

The paper presents a multimodal perturbation atlas using CRISPR knockouts in A549 cells, combining microscopy, phase imaging, and scRNA-seq to assess phenotypic resolution.

bioRxiv · Aug 25, 2026 · PreprintSystems Biology

Artifact-Minimized High-Ratio Image Compression with Preserved Analysis Fidelity

Bin Duan, Logan A. Walker, Bin Xie, Wei Jie Lee, Alexander Lin, Yan Yan, Dawen Cai

This paper develops a compression method that achieves high compression ratios with minimal visual and quantitative errors for single-molecule imaging data.

bioRxiv · Jul 17, 2024 · PreprintBioinformatics

An unbiased method to partition diverse neuronal responses into functional ensembles reveals interpretable population dynamics during innate social behavior

Alexander Lin, Cyril Selase Kwaku Akafia, Olga Dal Monte, Siqi Fan, Nicholas Fagan, Philip T. Putnam, Kay M. Tye, Steve W. C. Chang, Demba E. Ba, Stephen A. Allsop

The paper introduces a statistical framework to cluster neural activity into functional ensembles, demonstrating its application to social behavior data in rodents and primates.

bioRxiv · May 8, 2024 · PreprintNeuroscience

Incorporating Knowledge of Plates in Batch Normalization Improves Generalization of Deep Learning for Microscopy Images

Alexander Lin, Alex Xijie Lu

The paper introduces BEN, a method to correct batch effects in deep learning for microscopy images by aligning experimental and deep learning batches, improving model generalization.

bioRxiv · Oct 14, 2022 · PreprintBioinformatics