Author
Howard Hughes Medical InstituteORCID 0000-0001-6414-8627Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Celine Santiago, Julianna Siegrist, Nusrat Africawala…·David D. Ginty
This study shows that neuronal activity is essential for the development of touch receptors, as genetic disruption of Piezo2 and Nav1.6 leads to structural and functional defects in mechanosensory neurons.
Annie Handler, Qiyu Zhang, Song Pang…·David D. Ginty
This study uses 3D reconstructions of mechanosensory end organs to propose a unified mechanism for Aβ RA-LTMR activation through axon protrusions and Piezo2 distribution.
Lijun Qi, Michael Iskols, Annie Handler, David D. Ginty
This study identifies Krause corpuscles as vibrotactile sensors in the genitalia essential for normal sexual behavior in mice.
Shan Meltzer, Katelyn C. Boulanger, Emmanuella Osei-Asante…·David D. Ginty
Vicky Yao, Ammar Aly, Salina Kalik…·Revathy U. Chottekalapanda
This study identifies neuron-glia signaling mechanisms underlying the delayed antidepressant response to SSRIs in mice using single-cell sequencing.
Stephen Graf Brohawn, Weiwei Wang, Jürgen R. Schwarz…·Roderick MacKinnon
The paper shows TRAAK is localized to nodes of Ranvier and contributes to nerve conduction by modulating membrane potential and Na+ channel availability.