Author

Alexis N. Martinez

Instituto de Neurociencia Biomédica

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Claudio A. HetziD· 2 shared Alberto J. M. MartíniD· 1 shared Alejandra CatenaccioiD· 1 shared Carolina Jerez· 1 shared Claudia A. RiveraiD· 1 shared Claudio A. SotoiD· 1 shared Constanza González· 1 shared Cristian SaqueliD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Claudio A. HetzORCID

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2 papers

Recent·Most cited

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration

René L. Vidal, Denisse Sepúlveda, Paulina Troncoso-Escudero, Paula García-Huerta, Constanza González, Lars Plate, Carolina Jerez, José Cánovas, Claudia A. Rivera, Valentina Castillo, Marisol Cisternas-Olmedo, Sirley Leal, Alexis N. Martinez, Julia M. D. Grandjean, Sonia Donzelli, , Claudio A. Hetz

This study shows that forcing dimerization between ATF6f and XBP1s enhances UPR activity, reducing protein aggregation in neurodegenerative disease models.

Molecular Therapy · Feb 5, 2021Peer-reviewedNeuroscience

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

Maritza Oñate, Alejandra Catenaccio, Natalia Salvadores, Cristian Saquel, Alexis N. Martinez, Inés Moreno‐González, Nazaret Gamez, Paulina Rudolffi-Soto, Claudio A. Soto, Claudio A. Hetz, Felipe A. Court

This study shows that necroptosis mediates axonal degeneration in Parkinson's disease, suggesting it as a targetable pathway.

Cell Death and Differentiation · Oct 7, 2019Peer-reviewedNeuroscience