Author

Natalia Salvadores

Universidad MayorORCID 0000-0001-8700-8520Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandra CatenaccioiD· 1 shared Alejandro Rojas‐FernándeziD· 1 shared Alexis N. Martinez· 1 shared Claudio A. HetziD· 1 shared Claudio A. SotoiD· 1 shared Claudio Cappelli Leon· 1 shared Constanza Salinas-RebolledoiD· 1 shared Cristian SaqueliD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Alejandra CatenaccioORCID

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2 papers

Recent·Most cited

BiochemistryeLifePeer-reviewedNov 25, 2025

Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

Constanza Salinas-Rebolledo, Javier Blesa, Guillermo Valenzuela…·Alejandro Rojas‐Fernández

This paper describes the engineering of a PROTAC that uses p97-directed proteolysis to achieve specific substrate degradation without relying on E3 ubiquitin ligases.

3 citations

proteomicsexperimental assay

𝕏 PostBluesky

NeuroscienceCell Death and DifferentiationPeer-reviewedOct 7, 2019

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

Maritza Oñate, Alejandra Catenaccio, Natalia Salvadores…·Felipe A. Court

This study shows that necroptosis mediates axonal degeneration in Parkinson's disease, suggesting it as a targetable pathway.

129 citationstop 2%

mouseexperimental assay

𝕏 PostBluesky