Vascular and synaptic proteomes reveal blood-brain barrier disruption and postsynaptic remodeling in human temporal lobe epilepsy
Gavin Spillard, Mingzi Zhang, Nadia A. Atai, Allison Bosworth, Veronica A. Clementel, Jonathan Joseph Russin, Charles Yu Liu, Marcelo P. Coba, Ruslan Rust
This study identifies molecular changes in vascular and synaptic proteomes of human temporal lobe epilepsy, revealing BBB disruption and synaptic remodeling.
bioRxiv · Jun 16, 2026 · PreprintNeuroscience