Author

Allison Kleinstein

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Aayushi MahajaniD· 1 shared Abby L. Brand· 1 shared Angeliki MelaiD· 1 shared Athanassios Dovas· 1 shared Brent R. StockwelliD· 1 shared Brian Gill· 1 shared Jeffrey N. BruceiD· 1 shared Jia GuoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aayushi MahajanORCID

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1 paper

Recent·Most cited

IDH-mutant inhibitors enhance the sensitivity of IDH1-mutant gliomas to cysteine-methionine deprivation and ferroptosis

Angeliki Mela, Abby L. Brand, Aayushi Mahajan, Athanassios Dovas, Nelson Humala, Smriti Kanangat, Allison Kleinstein, Sandra Leskinen, Trang Tt Nguyen, Qiuqiang Gao, Pavan S. Upadhyayula, Jia Guo, Brian Gill, Markus David Siegelin, Peter A. Sims, , Peter Canoll

This study shows that IDH1-mutant glioma cells are more sensitive to cysteine-methionine deprivation and ferroptosis inducers, and that IDH inhibitors enhance this sensitivity.

bioRxiv · Feb 2, 2026 · PreprintCancer Biology