Author

Trang Thi Thu Nguyen

Columbia University Irving Medical CenterORCID 0000-0001-8747-9082Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:multiome· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Aayushi MahajaniD· 1 shared Abby L. Brand· 1 shared Allison Kleinstein· 1 shared An Nguyen· 1 shared Angeliki MelaiD· 1 shared Athanassios Dovas· 1 shared Brent R. StockwelliD· 1 shared Brian Gill· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Aayushi MahajanORCID

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2 papers

Recent·Most cited

IDH-mutant inhibitors enhance the sensitivity of IDH1-mutant gliomas to cysteine-methionine deprivation and ferroptosis

Angeliki Mela, Abby L. Brand, Aayushi Mahajan, Athanassios Dovas, Nelson Humala, Smriti Kanangat, Allison Kleinstein, Sandra Leskinen, Trang Tt Nguyen, Qiuqiang Gao, Pavan S. Upadhyayula, Jia Guo, Brian Gill, Markus David Siegelin, Peter A. Sims, , Peter Canoll

This study shows that IDH1-mutant glioma cells are more sensitive to cysteine-methionine deprivation and ferroptosis inducers, and that IDH inhibitors enhance this sensitivity.

bioRxiv · Feb 2, 2026 · PreprintCancer Biology

BBrowser: Making single-cell data easily accessible

Tri Le, Tan Phan, Minh Pham, Dat Tran, Loc Lam, Ngoc Tung Nguyen, Thao Truong, Hy Vuong, Tam Luu, Nam Phung, Ngan Pham, Trang Thi Thu Nguyen, Oanh Minh Pham, An Nguyen, Huy Tan Nguyen, , Son Truong Pham

A downloadable application pairs a curated single-cell database with a big-data analytics layer and a visualisation module for exploring single-cell omics data.

bioRxiv · Dec 11, 2020 · PreprintBioinformatics