Author

Amanda Seng

Chan Zuckerberg Biohub San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Michael BorjaiD· 2 shared Norma F NeffiD· 2 shared Ritwicq ArjyaliD· 2 shared Alejandro A. GranadosiD· 1 shared Alina NalyvaykoiD· 1 shared Andy ZhouiD· 1 shared Angela M. DetweileriD· 1 shared Angela Oliveira PiscoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Michael BorjaORCID

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2 papers

Recent·Most cited

How Mycobacterium tuberculosis builds a home: Single-cell analysis reveals M. tuberculosis ESX-1-mediated accumulation of anti-inflammatory macrophages in infected mouse lungs.

Weihao Zheng, Michael Borja, Leah C. Dorman, Jonathan Liu, Andy Zhou, Amanda Seng, Ritwicq Arjyal, Sara Sunshine, Alina Nalyvayko, Angela Oliveira Pisco, Oren S. Rosenberg, Norma F Neff, Beth Shoshana Zha

This study uses single-cell RNA sequencing to show that M. tuberculosis ESX-1 promotes the recruitment and differentiation of anti-inflammatory macrophages in infected mouse lungs.

Science Advances · Jan 15, 2025Peer-reviewedMicrobiology

Zebrahub-Multiome: Uncovering Gene Regulatory Network Dynamics During Zebrafish Embryogenesis

Yang Joon Kim, Shruthi VijayKumar, Benjamin Giovanni Iovino, Alejandro A. Granados, Sarah Ancheta, Max Frank, Xiang Zhao, Kyle Awayan, Amanda Seng, Michael Borja, Sheryl Paul, Honey E. Mekonen, Ritwicq Arjyal, Angela M. Detweiler, Yasin Şenbabaoğlu, , Löıc A. Royer

The paper presents Zebrahub-Multiome, a single-cell multiomic atlas of zebrafish embryogenesis, revealing gene regulatory network dynamics and cis-regulatory elements across developmental stages.

bioRxiv · Oct 18, 2024 · PreprintDevelopmental Biology