Weihao Zheng

This study shows that the local lung environment, not the peripheral environment, drives phenotypic diversity in monocyte-derived lung cells during Mtb infection.

The paper identifies impaired IFNγ responsiveness in CD11clo monocyte-derived lung cells as a mechanism allowing Mycobacterium tuberculosis persistence during chronic infection.

A vaccine using rare variable antigens (RVMA) reduces lung pathology in mice without lowering bacterial loads during Mtb infection.

This study uses single-cell RNA sequencing to show that M. tuberculosis ESX-1 promotes the recruitment and differentiation of anti-inflammatory macrophages in infected mouse lungs.

This paper develops an automated pipeline for fetal brain MRI analysis, including extraction, super-resolution, and 4D atlasing, to map fetal brain development in a Chinese population.

This paper describes a method to efficiently generate genetically modified primary human myeloid cells using CRISPR-Cas9 RNP nucleofection, demonstrating its utility in studying HIV-1 infection and myeloid cell biology.