Amy Leung

SEM-2/SoxC regulates multiple aspects of C. elegans postembryonic mesoderm development

This study identifies new functions of SEM-2/SoxC in C. elegans postembryonic mesoderm development, including its antagonistic relationship with LET-381 and regulation of HLH-8.

Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution compared to standard antibodies

This study compares the biodistribution of Fc-engineered molecules targeting BBB receptors with standard antibodies, showing distinct CNS and peripheral organ targeting.

Rapid and highly-specific generation of targeted DNA sequencing libraries enabled by linking capture probes with universal primers

This paper introduces a new targeted sequencing method called Linked Target Capture (LTC) that simplifies and accelerates library preparation while improving on-target read fractions and reducing sequencing costs.