Hypoxia pathway proteins regulate the synthesis and release of epinephrine in the mouse adrenal gland
Deepika Watts, Nicole Bechmann, Ana Meneses, Ioanna K. Poutakidou, Denise Kaden, Catleen Conrad, Anja Krüger, Johanna Stein, Ali El‐Armouche, Triantafyllos Chavakis, Graeme Eisenhofer, Mirko Peitzsch, Ben Wielockx
This study shows that PHD2-HIF2 pathway regulates epinephrine synthesis and release in mouse adrenal glands, linking hypoxia signaling to catecholamine production and systemic glucose levels.
bioRxiv · Oct 15, 2020 · PreprintMolecular Biology