Author

Denise Kaden

Technische Universität Dresden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Ali El‐ArmoucheiD· 3 shared Anja Krüger· 3 shared Ben WielockxiD· 3 shared Deepika WattsiD· 3 shared Mirko PeitzschiD· 3 shared Nicole BechmanniD· 3 shared Ana Meneses· 2 shared Graeme EisenhoferiD· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Ali El‐ArmoucheORCID

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3 papers

Recent·Most cited

HIF1α controls steroidogenesis under acute hypoxic stress

Stephen Ariyeloye, Deepika Watts, Mangesh T. Jaykar, Cagdas Ermis, Anja Krüger, Denise Kaden, Barbara Krystyna Stepien, Vasileia Ismini Alexaki, Mirko Peitzsch, Nicole Bechmann, Peter Mirtschink, Ali El‐Armouche, Ben Wielockx

This study investigates how HIF1α regulates steroidogenesis under acute hypoxia using cell lines, ex vivo models, and mice, finding HIF1α-dependent miRNA regulation and translational control of steroidogenic enzymes.

Cell Communication and Signaling · Feb 13, 2025Peer-reviewedMolecular Biology

Hypoxia pathway proteins regulate the synthesis and release of epinephrine in the mouse adrenal gland

Deepika Watts, Nicole Bechmann, Ana Meneses, Ioanna K. Poutakidou, Denise Kaden, Catleen Conrad, Anja Krüger, Johanna Stein, Ali El‐Armouche, Triantafyllos Chavakis, Graeme Eisenhofer, Mirko Peitzsch, Ben Wielockx

This study shows that PHD2-HIF2 pathway regulates epinephrine synthesis and release in mouse adrenal glands, linking hypoxia signaling to catecholamine production and systemic glucose levels.

bioRxiv · Oct 15, 2020 · PreprintMolecular Biology

HIF1α is an essential regulator of steroidogenesis in the adrenal gland

Deepika Watts, Johanna Stein, Ana Meneses, Nicole Bechmann, Aleš Neuwirth, Denise Kaden, Anja Krüger, Anupam N. Sinha, Vasileia Ismini Alexaki, Luis Gustavo Perez‐Rivas, Stefan Kircher, Antoine Martinez, Marily Theodoropoulou, Graeme Eisenhofer, Mirko Peitzsch, , Ben Wielockx

This study shows HIF1α is crucial for steroid hormone production in adrenal cells, with its absence increasing steroid levels and overexpression reducing them, affecting systemic health.

bioRxiv · Jul 8, 2020 · PreprintMolecular Biology