Cell BiologyMolecular Biology of the CellPeer-reviewed
Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
Celeste Riepe, Magda Wąchalska, Kirandeep K. Deol…·Ron R. Kopito
The paper identifies molecular machinery underlying CFTR-F508del ERAD and shows correctors stabilize RNF5-resistant folding states.
14 citations