Author

Ania Alik

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ronald MelkiiD· 3 shared Alexandra Barthelemy· 1 shared Birger Victor DieriksiD· 1 shared Blake HighetiD· 1 shared Carmen I. Nussbaum-KrammeriD· 1 shared Carolyn ShashaiD· 1 shared Chloé FriedrichiD· 1 shared Cyril CatelainiD· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

Ronald MelkiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pro-inflammatory role of granzyme K producing bystander CD8+ T cells in acute myeloid leukemia

Lisa Aziez, Nicolas Deredec, Ismaël Boussaid, Carolyn Shasha, Romain Vazquez, Chloé Friedrich, Ania Alik, Kanchanadevi Manasse, Zoé Fremont-Debaene, Alexandra Barthelemy, Cyril Catelain, Philippe Rameau, Marguerite Vignon, Justine Decroocq, Olivier Kosmider, , Yannick Simoni

This study identifies a pro-inflammatory role of Granzyme K-producing bystander CD8+ T cells in AML, which promote IL-8 secretion and may exacerbate disease progression.

bioRxiv · Aug 12, 2025 · PreprintImmunology

Dissecting aggregation and seeding dynamics of α-Syn polymorphs using the phasor approach to FLIM

Jessica Tittelmeier, Silke Druffel‐Augustin, Ania Alik, Ronald Melki, Carmen I. Nussbaum-Krammer

The paper uses FLIM to study α-Syn polymorphs in cells, showing distinct fluorescence lifetimes and differential processing by clearance pathways, leading to increased seeding capacity.

Communications Biology · Dec 7, 2022Peer-reviewedMolecular Biology

Human pericytes degrade alpha-synuclein aggregates in a strain-dependent manner

Birger Victor Dieriks, Blake Highet, Ania Alik, Tracy Bellande, Taylor J. Stevenson, Victoria F. Low, Thomas Park, Jason A. Correia, Patrick M. Schweder, Richard L. M. Faull, Ronald Melki, Maurice A. Curtis, Mike Dragunow

This study shows human pericytes degrade different strains of alpha-synuclein aggregates in vitro, with varying efficiency depending on the strain and origin of the pericytes.

bioRxiv · Jun 8, 2022 · PreprintNeuroscience

Impact of α-synuclein fibrillar strains and β-amyloid assemblies on mouse cortical neurons endo-lysosomal logistics

Qiao-Ling Chou, Ania Alik, François Marquier, Ronald Melki, François Treussart, Michel Simonneau

This study examines how α-synuclein and β-amyloid assemblies affect endosomal and lysosomal transport in mouse cortical neurons, revealing differential impacts on transport parameters and trajectory lengths.

eNeuro · Apr 25, 2022Peer-reviewedNeuroscience