ImmunologybioRxivPreprint
O-GlcNAcylation drives macrophage IL-4 responsiveness and tissue residency through metabolic and cell cycle calibration
Graham A. Heieis, Conor M. Finlay, Thiago A. Patente…·Bart Everts
3 citations
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Trinity College DublinORCID 0000-0001-8285-0903Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Graham A. Heieis, Conor M. Finlay, Thiago A. Patente…·Bart Everts
Heather Loughnane, Shrikanth Chomanahalli Basavarajappa, Anna Dominik…·Patrick T. Walsh
This study uses single-cell transcriptomics to show redox imbalance in coeliac duodenum, with decreased Nrf2 activation in key cell types, and demonstrates that Nrf2 activation reduces inflammation.