Engineered endothelial cell grafts form functional anastomoses and enable recruitment of intravenously delivered human T cells in CAM tumor models
A. Hartel, Anna Stettner, Jacob Mayer, Lea Amina Kalayci, Franziska Schneppenheim, Johannes Oldenburg, Heiko Rühl, Martin Fuhrmann, Tobias Bald, Johannes Brägelmann, Niklas Klümper, Marieta Ioana Toma, Felix Christopher Nebeling, René Hägerling, Michael Hölzel
This paper develops an endothelial graft-enhanced CAM tumor model to study T cell recruitment and activation in human cancer immunotherapy.
bioRxiv · Jul 17, 2026 · PreprintBioengineering