Emiliano P. Ricci

The paper develops iCoRD to rapidly deliver RNase H1 in live cells and shows it affects specific RNA:DNA hybrids and replication fork stability.

This study identifies SNX5/6 as essential partners for NCOA7-AS antiviral activity against influenza A virus and reveals the structural basis for their interaction.

This study identifies 104 cellular RNA-binding proteins within HIV-1 particles, revealing their role in viral gene expression and infectivity through interactions with HIV-1 genomic RNA.

The paper develops an improved method to capture ribosome-associated proteins and shows viral infections remodel these proteins in a virus-specific manner, with functional implications for viral propagation.

This study shows human MX1 restricts influenza A virus by sequestering vRNPs in cytoplasmic clusters via dynein and microtubules, reducing viral production.

This study shows that rapid delivery of RNase H1 rescues replication fork progression under stress without affecting R-loops.

This study uses ribosome profiling to identify conserved HIV-1 alternative open reading frames (ARFs) that encode T cell antigens, revealing new targets for vaccination.

The paper shows that mRNA decay during T cell activation occurs through translation-dependent and independent pathways, with ribosome density determining the pathway used.

This study identifies RSL24D1 as a key regulator of ribosome biogenesis and pluripotency in mouse embryonic stem cells, showing its role in maintaining self-renewal and suppressing differentiation.

The paper shows that ribosomes guide piRNA production from mRNAs in 3UTRs after translating upstream long ORFs, revealing a conserved mechanism for piRNA biogenesis.

The paper identifies TADs as functional units in DDR, showing cohesin-mediated loop extrusion contributes to {gamma}H2AX/53BP1 domain formation during DSB repair.

This study shows that SenataxinSen1 promotes RNA Polymerase III transcription termination in fission yeast independently of R-loops.

This study shows mutant huntingtin (mHtt) stalls ribosomes and suppresses protein synthesis independently of FMRP, using ribosome profiling in HD cells and mouse models.

The paper investigates how RNA-binding proteins (RBPs) change in response to viral infection and identifies RBPs crucial for viral replication.