Author

April Cockburn

Pennsylvania State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Organism:mouse· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alexander Q. WixomiD· 3 shared Amber Miller· 3 shared Belinda M. GiardineiD· 3 shared Cheryl A. KelleriD· 3 shared David M. BodineiD· 3 shared Elisabeth F. HeustoniD· 3 shared Gerd A. BlobeliD· 3 shared Ross C. HardisoniD· 3 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Alexander Q. WixomORCID

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3 papers

Recent·Most cited

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

Guanjue Xiang, Xi He, Belinda M. Giardine, Kathryn J. Isaac, Dylan J. Taylor, Rajiv C. McCoy, Camden S. Jansen, Cheryl A. Keller, Alexander Q. Wixom, April Cockburn, Amber Miller, Qian Qi, Yanghua He, Yichao Li, Jens Lichtenberg, , Ross C. Hardison

This study identifies conserved and species-specific cis-regulatory elements in human and mouse blood cells using integrative epigenomic analysis and clustering.

Genome Research · Jul 1, 2024Peer-reviewedGenomics

Effects of sheared chromatin length on ChIP-seq quality and sensitivity

Cheryl A. Keller, Alexander Q. Wixom, Elisabeth F. Heuston, Belinda M. Giardine, Chris C.‐S. Hsiung, Maria Long, Amber Miller, Stacie M. Anderson, April Cockburn, Gerd A. Blobel, David M. Bodine, Ross C. Hardison

This study investigates how chromatin shearing affects ChIP-seq quality and shows that sonication levels significantly impact signal quality and specificity for different transcription factors.

G3 Genes Genomes Genetics · Mar 31, 2021Peer-reviewedGenomics

An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis

Guanjue Xiang, Cheryl A. Keller, Elisabeth F. Heuston, Belinda M. Giardine, Lin An, Alexander Q. Wixom, Amber Miller, April Cockburn, Michael E.G. Sauria, Kathryn J. Isaac, Jens Lichtenberg, Berthold Göttgens, Qunhua Li, David M. Bodine, Shaun Mahony, , Ross C. Hardison

The paper integrates epigenomic and transcriptomic data from mouse hematopoiesis to identify regulatory elements and their dynamics across cell types.

Genome Research · Mar 1, 2020Peer-reviewedGenomics