Projection-Targeted Photopharmacology Reveals Distinct Anxiolytic Roles for Presynaptic mGluR2 in Prefrontal- and Insula-Amygdala Synapses
Hermany Munguba, Ipsit Srivastava, Vanessa A. Gutzeit, Ashna Singh, Akshara Vijay, Melanie Kristt, Anisul Arefin, Sonal Thukral, Johannes Broichhagen, Joseph M. Stujenske, Conor M. Liston, Joshua Levitz
The paper uses photopharmacology to show that mGluR2 in specific brain projections regulates distinct anxiety-related behaviors.
bioRxiv · Jan 15, 2024Neuroscience