Roberto A. Ribas

This study shows systemic hypoxia promotes lung adenocarcinoma progression by mobilizing glycogen via GAA, supporting tumor growth through metabolic remodeling.

The paper maps spatial metabolome coherence across mouse brain regions using MALDI imaging and optimal transport, showing preserved coherence in Alzheimer's model despite metabolic changes and demonstrating intervention effects.

This study identifies hyper-glycosylation as a driver of Alzheimer's disease through metabolic analysis and interventions, showing its impact on cognitive decline and mortality.

The paper shows that PV-INs have unique metabolic specializations lost after TBI, which can be rescued by 2-deoxyglucose, and identifies PGC-1α and lncRNAs as key factors in this dysfunction.

MetaVision3D converts serial 2D MALDI mass spectrometry imaging sections into a 3D spatial metabolome atlas using computer vision techniques.

The paper presents a method for simultaneous spatial analysis of metabolome, lipidome, and glycome from a single tissue section using mass spectrometry imaging and a computational framework called Sami.