Author

B. A. C. Harley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 6

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Organism:human· 4 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

S. G. Zambuto· 2 shared A. E. Gilchrist· 1 shared A. S. Tiffany· 1 shared C. J. Hunter· 1 shared D. T. Yamaguchi· 1 shared G. Dveksler· 1 shared G. K. Jalandhra· 1 shared J. C. Lee· 1 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBioengineering

S. G. Zambuto

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Beta-Catenin Limits Osteogenesis on Regenerative Materials in a Stiffness-Dependent Manner

Q. Zhou, X. Ren, M. K. Oberoi, R. M. Caprini, M. J. Dewey, V. Kolliopoulos, D. T. Yamaguchi, B. A. C. Harley, J. C. Lee

This study shows that beta-catenin limits osteogenesis on stiff nanoparticulate mineralized collagen glycosaminoglycan scaffolds by modulating Wnt and mechanotransduction pathways.

bioRxiv · Jun 15, 2021Bioengineering

Hydrogels Containing Gradients in Vascular Density Reveal Dose-Dependent Role of Angiocrine Cues on Stem Cell Behavior

M. T. Ngo, V. R. Barnhouse, A. E. Gilchrist, C. J. Hunter, J. N. Hensold, B. A. C. Harley

This study uses 3D hydrogels with vascular density gradients to show how angiocrine cues affect HSC behavior, finding that high vessel density reduces Akt signaling and increases lineage-positive cell expansion.

bioRxiv · Feb 12, 2021Bioengineering

The role of pregnancy-specific glycoproteins on trophoblast motility in three-dimensional gelatin hydrogels

S. G. Zambuto, S. Rattila, G. Dveksler, B. A. C. Harley

This study investigates how pregnancy-specific glycoproteins (PSG1 and PSG9) affect trophoblast motility in 3D gelatin hydrogels, showing PSG9 reduces motility while PSG1 increases it.

bioRxiv · Sep 25, 2020 · PreprintBioengineering

Freeform printing of heterotypic tumor models within cell-laden microgel matrices

T. G. Molley, G. K. Jalandhra, S. R. Nemec, A. S. Tiffany, B. A. C. Harley, T.-t. Hung, K. A. Kilian

This paper introduces a bioprinting method to create complex tumor microenvironments with vasculature and multiple cell types, showing tumor cell migration into the vasculature.

bioRxiv · Aug 30, 2020 · PreprintBioengineering

Tuning trophoblast invasion in a gelatin hydrogel via soluble cues from the maternal-fetal interface

S. G. Zambuto, K. B. H. Clancy, B. A. C. Harley

This study uses a 3D gelatin hydrogel model to investigate how maternal-fetal interface cues affect trophoblast invasion and viability, showing responses to EGF, TGFβ1, and cortisol.

bioRxiv · Apr 16, 2020Bioengineering

The influence of cyclic tensile strain on multi-compartment collagen-GAG scaffolds for tendon-bone junction regeneration

W. K. Grier, R. A. Sun Han Chang, M. D. Ramsey, B. A. C. Harley

This study applies cyclic tensile strain to a collagen-GAG scaffold to enhance regeneration of tendon-bone junctions by promoting spatially distinct stem cell differentiation.

bioRxiv · Sep 3, 2018Bioengineering