Author

T. G. Molley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:development & morphogenesis· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

K. A. Kilian· 4 shared G. K. Jalandhra· 2 shared A. A. Abdeen· 1 shared A. S. Tiffany· 1 shared A. Yeola· 1 shared B. A. C. Harley· 1 shared C. D. Ranaweera· 1 shared C. H. Seward· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersBioengineering

K. A. Kilian

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Author profile →

5 papers

Recent·Most cited

Enzyme Bioink for the 3D Printing of Biocatalytic Materials

L. A. Altevogt, R. H. Sheikh, T. G. Molley, J. Yong, K. Liang, P. Spicer, K. A. Kilian, P. R. Wich

This paper develops a biocatalytic enzyme bioink for 3D printing that enhances the biochemical activity of printed constructs by covalently attaching horseradish peroxidase to a gelatin methacrylate scaffold.

bioRxiv · Feb 4, 2024 · PreprintBioengineering

Gas modulating microcapsules for spatiotemporal control of hypoxia

t. G. molley, S. Jiang, C. Kopecky, C. D. Ranaweera, G. K. Jalandhra, J. Rnjak-Kovacina, K. A. Kilian

This paper develops microcapsules that control oxygen levels in cell cultures and tissues, showing their ability to modulate hypoxia signaling and promote neovascularization.

Proceedings of the National Academy of Sciences · Apr 11, 2023Peer-reviewedBioengineering

Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells

P. Srivastava, S. Romanazzo, J. Ireland, S. Nemec, T. G. Molley, P. Jayathilaka, E. Pandzic, A. Yeola, V. Chandrakanthan, J. Pimanda, K. Kilian

This study shows that microconfinement of pluripotent stem cells on hydrogels triggers gastrulation-like events without exogenous factors, leading to primitive streak formation and lineage specification.

bioRxiv · Oct 28, 2021Bioengineering

Freeform printing of heterotypic tumor models within cell-laden microgel matrices

T. G. Molley, G. K. Jalandhra, S. R. Nemec, A. S. Tiffany, B. A. C. Harley, T.-t. Hung, K. A. Kilian

This paper introduces a bioprinting method to create complex tumor microenvironments with vasculature and multiple cell types, showing tumor cell migration into the vasculature.

bioRxiv · Aug 30, 2020 · PreprintBioengineering

Geometric regulation of histone state directs melanoma reprogramming

J. Lee, T. G. Molley, C. H. Seward, A. A. Abdeen, H. Zhang, X. Wang, H. Gandhi, J.-L. Yang, K. Gaus, K. A. Kilian

This study identifies a link between geometric features of melanoma aggregates and reprogramming to stem cell-like initiating cells through histone modifications.

bioRxiv · Dec 11, 2019Cancer Biology