RAD-TGTs: Measurement of cellular tensions via flow cytometry and DNA sequencing enabled by force-dependent rupture and delivery of DNA tension probes
M. R. Pawlak, A. T. Smiley, M. D. Kelly, G. A. Shamsan, S. M. Anderson, B. A. Smeester, D. A. Largaespada, D. J. Odde, W. R. Gordon
The paper introduces RAD-TGTs, a method to measure cellular tensions using DNA duplexes that rupture under force, with readout via flow cytometry and DNA sequencing.
bioRxiv · Nov 8, 2022 · PreprintBiophysics