R. Garcia-Milian

Asparagine synthetase and G-protein coupled estrogen receptor are critical responders to nutrient supply in KRAS mutant colorectal cancer

This study investigates how nutrient supply affects ASNS and GPER1 expression in KRAS mutant and wild-type colorectal cancer cells and their association with patient survival.

Autologous humanized PDX modeling for immuno-oncology recapitulates the human tumor microenvironment

This study develops an autologous humanized PDX model to study tumor-immune interactions and demonstrates its utility in preclinical testing by showing VEGF-A inhibition reduces tumor growth.

Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

This study shows that aged bone marrow-derived cells increase smooth muscle cell polyclonality in atherosclerotic plaques through reduced TET2 and increased TNF signaling.

Peer teaching as bioinformatics training strategy: incentives, challenges, and benefits.

This study evaluates peer teaching workshops as a bioinformatics training strategy, identifying benefits like improved communication skills and challenges like time constraints and classroom management.

Novel insights into the mode of action of 1,4-dioxane using a systems screening approach

This study investigates the toxic effects of 1,4-dioxane in mice using histopathology and multi-omics approaches, finding DNA damage counterbalanced by repair mechanisms with no systemic metabolic impact.

Molecular pathway analysis indicates a distinct metabolic and immune phenotype in women with right-sided colon cancer

This study identifies a distinct metabolic and immune phenotype in women with right-sided colon cancer through gene expression analysis of public datasets.