Author

B. Duncan-Lowey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. G. Johnson· 2 shared G. Amitai· 2 shared M. L. Mayer· 2 shared P. J. Kranzusch· 2 shared R. Sorek· 2 shared A. Kacen· 1 shared A. Millman· 1 shared E. Yirmiya· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

A. G. Johnson

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2 papers

Recent·Most cited

Cryo-EM structure of the RADAR supramolecular anti-phage defense complex

B. Duncan-Lowey, N. Tal, A. G. Johnson, S. Rawson, M. L. Mayer, S. Doron, A. Millman, S. Melamed, T. Fedorenko, A. Kacen, G. Amitai, R. Sorek, P. J. Kranzusch

The paper determines the cryo-EM structure of the RADAR complex, showing RdrB targets mononucleotides and catalyzes ATP-to-ITP conversion to limit phage replication.

Cell · Mar 1, 2023Peer-reviewedBiochemistry

Bacterial gasdermins reveal an ancient mechanism of cell death

A. G. Johnson, T. Wein, M. L. Mayer, B. Duncan-Lowey, E. Yirmiya, Y. Oppenheimer-Shaanan, G. Amitai, R. Sorek, P. J. Kranzusch

This study identifies bacterial gasdermin homologs that execute prokaryotic cell death via caspase-like protease activation, revealing an ancient mechanism of regulated cell death shared with animals.

bioRxiv · Jun 7, 2021Microbiology