T. Wein

CARD-like domains mediate anti-phage defense in bacterial gasdermin systems

This study identifies CARD-like domains in bacterial defense systems that activate gasdermin-mediated cell death against phage infection.

Denitrification in foraminifera has ancient origin and is complemented by associated bacteria

The paper shows denitrification genes are conserved in foraminifera and their microbiome complements the pathway, revealing an ancient origin of this trait in these organisms.

Bacterial gasdermins reveal an ancient mechanism of cell death

This study identifies bacterial gasdermin homologs that execute prokaryotic cell death via caspase-like protease activation, revealing an ancient mechanism of regulated cell death shared with animals.

Protozoa populations are ecosystem engineers that shape prokaryotic community structure and function of the rumen microbial ecosystem

This study shows that protozoa in the rumen significantly influence prokaryotic community structure and function, including methane production and diversity.

The effect of population bottleneck size and selective regime on genetic diversity and evolvability in bacteria

This study shows that temperature has a stronger effect on genetic diversity and fitness in bacteria than population bottleneck size following bottlenecks.

Segregational drift and the interplay between plasmid copy number and evolvability

This study shows that segregational drift in multicopy plasmids reduces their evolvability by increasing mutation loss and fixation time, despite higher mutational supply.