Author

B. J. Wick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

B. R. Webber· 2 shared B. S. Moriarity· 2 shared N. J. Slipek· 2 shared E. J. Pomeroy· 1 shared E. Kleinboehl· 1 shared J. B. Krueger· 1 shared J. D. Jensen· 1 shared J. G. Skeate· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

B. R. Webber

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Engineering Memory T Cells as a platform for Long-Term Enzyme Replacement Therapy in Lysosomal Storage Disorders

E. Kleinboehl, K. Laoharawee, J. D. Jensen, J. J. Peterson, N. J. Slipek, B. J. Wick, M. J. Johnson, B. R. Webber, B. S. Moriarity

This study demonstrates that genetically engineered memory T cells can deliver enzyme replacement therapy for mucopolysaccharidosis type I, reducing GAG levels in multiple tissues for up to 22 weeks.

bioRxiv · Apr 23, 2024 · PreprintBioengineering

Non-Viral Engineering of CAR-NK and CAR-T cells using the Tc Buster Transposon System™

E. J. Pomeroy, W. S. Lahr, J. W. Chang, J. B. Krueger, B. J. Wick, N. J. Slipek, J. G. Skeate, B. R. Webber, B. S. Moriarity

This paper demonstrates a non-viral method using the Tc Buster transposon system to deliver CAR constructs to primary human NK and T cells, achieving efficient gene expression and functional activity.

bioRxiv · Aug 2, 2021 · PreprintBioengineering