Author

K. Laoharawee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

B. R. Webber· 2 shared B. S. Moriarity· 2 shared N. J. Slipek· 2 shared A. K. Gilkey· 1 shared B. J. Wick· 1 shared E. J. Eaton· 1 shared E. J. Pomeroy· 1 shared E. Kleinboehl· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioengineering

B. R. Webber

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Engineering Memory T Cells as a platform for Long-Term Enzyme Replacement Therapy in Lysosomal Storage Disorders

E. Kleinboehl, K. Laoharawee, J. D. Jensen, J. J. Peterson, N. J. Slipek, B. J. Wick, M. J. Johnson, B. R. Webber, B. S. Moriarity

This study demonstrates that genetically engineered memory T cells can deliver enzyme replacement therapy for mucopolysaccharidosis type I, reducing GAG levels in multiple tissues for up to 22 weeks.

bioRxiv · Apr 23, 2024 · PreprintBioengineering

Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing

M. Wang, J. B. Krueger, A. K. Gilkey, E. M. Stelljes, M. G. Kluesner, E. J. Pomeroy, J. G. Skeate, N. J. Slipek, W. S. Lahr, P. N. Claudio Vazquez, Y. Zhao, E. J. Eaton, K. Laoharawee, B. R. Webber, B. S. Moriarity

This study enhances CAR-NK cell functionality using non-viral base editing and transposon integration, showing improved therapeutic potential in Burkitt's lymphoma models.

bioRxiv · Mar 5, 2024Bioengineering