Z. Gerhart-Hines

The paper shows FFA4, a GPCR, signals from lipid droplet-associated membranes in adipocytes, providing localized feedback to regulate lipolysis.

This study shows that Nfe2l1 regulates skeletal muscle proteostasis and function, with its loss causing muscle fiber type switching and insulin resistance in high-fat diet conditions.

This study shows mitochondrial phosphatidylethanolamine directly regulates UCP1 to control thermogenesis in brown adipose tissue.

This study shows that a compromised epidermal barrier increases energy expenditure, food intake, and white adipose tissue browning while preventing diet-induced obesity.

This study shows that housing mice at thermoneutral temperatures reduces exercise training benefits in metabolic parameters and tissue adaptations.

The paper compares the secretomes of human brown and white adipocytes using proteomics, identifying EPDR1 as a novel batokine involved in thermogenesis and energy consumption.