The proteasome maturation factor POMP moonlights as a stress-induced transcriptional regulator
Stefano L. Giandomenico, M.P. Mueller, Marc van Oostrum, Kristina Desch, B. Krause, Georgi Tushev, Elena Ciirdaeva, Julian D. Langer, Beatriz Alvarez‐Castelao, Erin Margaret Schuman
This study identifies POMP as a stress-induced transcriptional regulator that buffers proteasome dysfunction through a non-canonical role in nucleolar RNA processing.
bioRxiv · Apr 25, 2025 · PreprintBiochemistry