Author

B. L. Bass

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Organism:Drosophila· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. M. Aderounmu· 2 shared P. J. Aruscavage· 2 shared B. Kolaczkowski· 1 shared C. D. Consalvo· 1 shared D. M. Eckert· 1 shared E. Leslie· 1 shared H. M. Donelick· 1 shared M. Jonely· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. M. Aderounmu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA

C. D. Consalvo, A. M. Aderounmu, H. M. Donelick, P. J. Aruscavage, D. M. Eckert, P. S. Shen, B. L. Bass

The paper investigates how C. elegans Dicer collaborates with DRH-1 and RDE-4 to cleave dsRNA, revealing their roles in antiviral defense mechanisms.

bioRxiv · Sep 21, 2023 · PreprintBiochemistry

Ancestral protein reconstruction reveals evolutionary events governing variation in Dicer helicase function

A. M. Aderounmu, P. J. Aruscavage, B. Kolaczkowski, B. L. Bass

This study uses ancestral protein reconstruction to show that vertebrate Dicer lost ATP hydrolysis function due to reduced dsRNA affinity, not just active site mutations.

bioRxiv · Dec 30, 2022Biochemistry

A real-time, transient kinetic study of Drosophila melanogaster Dicer-2 elucidates mechanism of termini-dependent cleavage of dsRNA.

R. K. SINGH, M. Jonely, E. Leslie, N. A. Rejali, R. Noriega, B. L. Bass

This study investigates the kinetic mechanism of Drosophila Dicer-2 processing dsRNA with different termini using stopped-flow and fluorescence techniques, revealing ATP-dependent conformational changes and cleavage dynamics.

bioRxiv · Sep 29, 2020Biophysics