Author

B. Lecka-Czernik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Assay:clinical cohort / trial· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

P. J. Czernik· 3 shared S. Baroi· 3 shared A. Chougule· 2 shared A. Abokor· 1 shared B. Joe· 1 shared B. Mell· 1 shared B. S. Yeoh· 1 shared C. J. Rosen· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersPhysiology

P. J. Czernik

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3 papers

Recent·Most cited

PPARG in osteocytes controls cell bioenergetics and systemic energy metabolism independently of sclerostin levels in circulation

S. Baroi, P. J. Czernik, M. Khan, J. Letson, E. Crowe, A. Chougule, P. R. Griffin, C. J. Rosen, B. Lecka-Czernik

This paper shows that PPARG in osteocytes regulates bioenergetics and systemic energy metabolism in mice, independent of sclerostin levels, with sex-specific effects on mitochondrial function and insulin signaling.

bioRxiv · Apr 4, 2024Physiology

PPARG in osteocytes is essential for sclerostin expression, bone mass, marrow adiposity and TZD-induced bone loss

S. Baroi, P. J. Czernik, A. Chougule, P. Griffin, B. Lecka-Czernik

bioRxiv · Sep 13, 2020Physiology

Reconstitution of the host holobiont in germ-free rats acutely increases bone growth and affects marrow cellular content

P. J. Czernik, R. M. Golonka, S. Chakraborty, B. S. Yeoh, A. Abokor, P. Saha, J. Y. Yeo, B. Mell, X. Cheng, S. Baroi, B. Joe, M. Vijay-Kumar, B. Lecka-Czernik

This study shows that reconstituting the gut microbiota in germ-free rats accelerates bone growth and alters marrow cell composition, with effects linked to increased short-chain fatty acids and IGF-1 levels.

bioRxiv · Jul 15, 2020 · PreprintPhysiology