Author

B. R. Roberts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Gokhale· 2 shared C. Xu· 2 shared E. Werner· 2 shared V. Faundez· 2 shared Z. Wen· 2 shared A. Barrientos· 1 shared A. Crocker· 1 shared A. Ivanova· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

A. Gokhale

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacological and behavioral effects of tryptamines present in psilocybin-containing mushrooms

R. J. Rakoczy, G. N. Runge, A. K. Sen, O. Sandoval, Q. Nguyen, B. R. Roberts, J. H. Sciortino, W. J. Gibbons, L. M. Friedberg, J. A. Jones, M. S. McMurray

This study compares the pharmacological and behavioral effects of tryptamines in psilocybin-containing mushrooms, finding that norbaeocystin may have therapeutic potential similar to psilocybin without causing hallucinations.

bioRxiv · Oct 19, 2023Pharmacology & Toxicology

APOE Expression and Secretion are Modulated by Mitochondrial Dysfunction

M. E. Wynne, O. Ogunbona, A. R. Lane, A. Gokhale, S. A. Zlatic, C. Xu, Z. Wen, D. Duong, S. Rayaprolu, A. Ivanova, E. A. Ortlund, E. B. Dammer, N. T. Seyfried, B. R. Roberts, A. Crocker, , V. Faundez

This study shows mitochondrial dysfunction increases APOE expression and secretion in multiple cell types and models, linking mitochondrial health to Alzheimer's disease risk.

bioRxiv · May 11, 2022Cell Biology

The Mitochondrial RNA Granule Modulates Manganese-Dependent Cell Toxicity

E. Werner, A. Gokhale, M. Ackert, C. Xu, Z. Wen, A. M. Roberts, B. R. Roberts, A. R. Vrailas-Mortimer, A. J. Crocker, V. Faundez

This study identifies the mitochondrial RNA granule as a protective mechanism against manganese toxicity by showing its downregulation enhances cell survival.

bioRxiv · Jan 4, 2022Cell Biology